Few single nucleotide variations in exomes of human cord blood induced pluripotent stem cells.
The effect of the cellular reprogramming process per se on mutation load remains unclear.To address this issue, we performed whole exome sequencing analysis of induced pluripotent stem cells (iPSCs) reprogrammed from safety switch human cord blood (CB) CD34(+) cells.Cells from a single donor and improved lentiviral vectors for high-efficiency (2-14